Who I am

Biostatistician and machine-learning researcher with an M.D. and a research background in neuroscience. I work on statistical analysis and automated data workflows for clinical development, and on machine-learning problems in computational biology and scientific computing.

Projects

  • Python

    CayleyPy

    Collaborative open-source research project on AI-assisted pathfinding and computation on large Cayley graphs. My spin-off: MLPermutationSolver, a GPU-accelerated PyTorch implementation of ML-guided beam search.

  • Python

    Abbreviator

    Django app for managing and auditing abbreviations in .docx files; uses a fine-tuned Llama 3.2 model for medical-context suggestions.

  • R

    ClinicalSampleSizePlanner

    Shiny app for clinical trial sample size calculation (currently bioequivalence; extensible to other designs).

Core tools

R Python PyTorch Scikit-learn XGBoost LightGBM Transformers LLM fine-tuning Shiny Django Git
Publications and research outputs

Peer-reviewed journal articles (14)

  1. CayleyPy RL: Pathfinding and reinforcement learning on Cayley graphs . Advances in Theoretical and Mathematical Physics, 2026.
  2. Meta-analysis of the effects of anti-migraine therapeutics in the rat trigeminovascular nociception model as a tool for design optimization . European Journal of Neuroscience, 2023.
  3. Bioequivalence study of generic nirmatrelvir in healthy volunteers . Pharmacy & Pharmacology, 2023.
  4. Characteristics of olokizumab pharmacokinetics in patients with novel coronavirus infection COVID-19 . Pharmacy & Pharmacology, 2022.
  5. Olokizumab reduces the risks of death in hospitalized patients with moderate and severe COVID-19 . Infectious Diseases: News, Opinions, Training, 2022.
  6. The implementation of transcranial Doppler ultrasonography for preclinical study of migraine . Canadian Journal of Physiology and Pharmacology, 2022.
  7. Electrophysiological model of trigeminovascular nociception as a tool for experimental study of migraine pharmacotherapy . Russian Journal of Pain, 2021.
  8. A systematic review and meta-analysis of cannabis-based medicines, cannabinoids and endocannabinoid system modulators tested for antinociceptive effects in animal models . Pain, 2021.
  9. Differential effects of the Piezo1 agonist Yoda1 in the trigeminovascular system . Experimental Neurology, 2021.
  10. The influence of metoclopramide on trigeminovascular nociception . Neuroscience, 2020.
  11. The action of TAAR1 agonist RO5263397 on executive functions in rats . Cellular and Molecular Neurobiology, 2020.
  12. Activation of trace amine-associated receptor 1 attenuates schedule-induced polydipsia in rats . Neuropharmacology, 2019.
  13. Trace Amine-Associated Receptor 1 modulates the locomotor and sensitization effects of nicotine . Frontiers in Pharmacology, 2018.
  14. Possible approaches to CYP2C9-guided prescription of sulfonylureas in Russia . Pharmacogenomics, 2016.

Preprints and workshop papers